Monday, February 3, 2014

DNA of peanut-allergic kids changes with immune therapy

For peanut allergic people
The most common type of allergies come from food allergies, and to most kids it is not fun to be allergic to foods you are supposed to enjoy in a young age. The peanut allergy is probably the most common allergy, and if allergic people come in contact with peanuts the side effects and consequences are severe. It is definitely a matter of concern due to the fact that the United States is one of the major producers of peanut products. The famous peanut butter, that is incredibly popular in America, is loved by many people and the largest age group that enjoys this product are the children. Growing up the peanut butter and jelly sandwiches were the food that summarizes most people´s childhood and to the kids and people that are allergic to peanuts do not share this memory. Being deprived from this supplement because of allergic reactions was a kids worst nightmare especially if peanuts contain many nutrients and oils that the body needs. But now kids that are allergic to peanuts have the opportunity of becoming immune to it and eat this food without any risk. 

Treating a peanut allergy with oral immunotherapy changes the DNA of the patient's immune cells, according to a new study from the Stanford University School of Medicine and Lucile Packard Children's Hospital Stanford.Scientists are conducting clinical trials of doctor-supervised immunotherapy, in which peanut-allergic patients take increasing amounts of peanut powder to try to desensitize them to the peanut allergen. "At first, eating two peanut butter cups a day might seem fun, but it gets a little boring and a lot of people might stop," said Kari Nadeau, MD, PhD, associate professor of pediatrics at Stanford and an immunologist at Stanford Hospital & Clinics and Lucile Packard Children's Hospital Stanford.The patients were asked to stop eating peanuts for three months and then were given a small amount of peanut powder to see if their allergy returned.Patients who maintained their tolerance to peanuts had low levels of DNA methylation at FOXP3, while those who regained their allergy had an intermediate level.Peanut-allergic patients who had not received oral immunotherapy (the control group) had a high level of DNA methylation at the FOXP3 gene.

Peanuts are a food that the majority of people enjoy, and the people who are banned from eating it because it can harm their health and can kill them because of an allergic reaction have now an opportunity. I believe it is innovating how now the most simple problems as being allergic to something can be reverted, especially if you are born having that allergy. Medical innovations have made the consumption of a standard food item reality for children and people that have a reaction in a small doses. This process that makes people immune to their allergies is groundbreaking and it is very impressive how now people have more access and options to things that in one point was dangerous to their bodies. I believe this is outstanding and I support the medical innovations occurring in our time that will lead us to a better future.